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CMS - 2.2.10 - Spuzzum

PG Education


The department offers M. Sc. in Genetics.

Eligibility for Admissions

Students of B.Sc. (General) or B.Sc. (Hons.) or an equivalent undergraduate degree in any branch oflife-sciences/physical-sciences/chemical-sciences/mathematical-sciences/medical-sciences/pharmacology/any branch of biology/paramedical sciences. The candidate should have scored 60% (or equivalent CGPA score) marks in their main subject (for Hons. stream) or in aggregate (for B.Sc General) or other equivalent undergraduate degree. Relaxation in eligibility will be as per university guidelines.

Admission in M.Sc. (Genetics) is through an entrance test consisting of Multiple Choice Questions based on various sub-disciplines of biological sciences (B.Sc. level) i.e. Botany, Zoology, Biochemistry, Microbiology, Biotechnology etc. with emphasis on Genetics. Some questions from basics in Chemistry, Physics, Mathematics and General Awareness may also be included.

Programme Objectives (POs)

This program is aimed at graduate students from any field of science who want to pursue research careers in specialized area of biological science. The program focuses at developing strong foundational skill in various fields of genetics. In addition to fundamentals, the students are exposed to core areas in Molecular Genetics (microbial, Drosophila, plants and humans) as well as related areas like Biochemistry, Biostatistics, Developmental Biology, Recombinant DNA Technology and Computer Applications. Apart from the core courses, students can select few courses of their preference from a bunch of elective courses. Special emphasis is given on intensive lab practical sessions, as well as hands on for bioinformatics data analysis where every student gets a chance to independently perform the experiments and gain experience with standard molecular biology and genetic tools. Class room seminars, discussions, written tests, project work and hands on practical training are integral components of the course. The syllabus is updated regularly to reflect the important advances in the related field. Students are continuously evaluated during the course. Various scholarships viz., Merit Scholarship, All India Post Graduate Scholarship and Monsanto Post Graduate Scholarship are also available for the M.Sc. students. Students are encouraged to clear UGC/CSIR-NET while pursuing their M.Sc. course.

Programme Specific Outcomes (PSOs)

GENCC101 Introduction to Genetics
Genetic analysis is studied with reference to reverse and forward genetics and use of phenotypic, biochemical and molecular markers. Emphasis is laid on sources of genetic variation, which forms the basis of understanding diversity in a population.

GENCC102 Chromosome, Genes and Genomes
This course has been designed to provide a comprehensive notion about the dynamic nature of chromosome and its influence in regulating cellular functioning and organism as whole. The students would also develop a holistic concept about genome organization, various gene mapping strategies and the genetic elements present in genome. Emphasis would be given to explain the topics with the help of interactive classroom sessions including classical experimental strategies, examples from different model organisms and contemporary genetic approaches and methods.

GENCC103 Cell Biology
The course is geared to impart a basic understanding about cell structure and organization, transport of biomolecules in eukaryotes, checks and balances during stress, signal transduction, crosstalk between basic processes and cell cycle, and basics on programmed cell death.

GENCC104 Molecular Biology
The students will learn DNA structure, basic processes of replication, transcription, translation and their mechanisms in both prokaryotes and eukaryotes. They will also be introduced to regulation of biochemical pathways and networks with special attention to physiological conditions such as stress, exercise and starvation as well as diseased conditions such as diabetes.

GENCC105 Experiments in Genetics-I (Practicals based on theory)
Experimental and hands-on knowledge on bacterial culture, mutagenesis, setting of genetic crosses using various mutant lines of Drosophila, three-point linkage mapping, studying chromosomal aberration, protein estimation and enzyme kinetics, SDS-PAGE analysis etc.

GENCC201 Population, evolutionary and quantitative genetics
Forces that have an impact on levels of genetic variations in natural and/or experimental populations for both qualitative and quantitative traits, and the tools to study these traits are taught.

GENCC202 Bioinformatics and Biostatistics
This course is aimed at imparting knowledge of application of computational methods in order to address biological problems. Web-based programs to obtain and manipulate biological data (both sequence and structure) are taught to highlight sequence-structure-function relationship to further understanding of biological systems.

GENCC203 Regulation of Gene Expression
Gene expression that is regulated at various stages of transcription, translation and post- translation and epigenetic regulation are taught by using examples from various model organisms.

GENCC204 Recombinant DNA Technology
This paper provides the details of the various techniques and tools used as well as their application in the generation of commercial products of myriad usage (Biotechnology).

GENCC205 Experiments in Genetics- II (Practicals based on theory)
With these set of practicals, students learn the basic Recombinant DNA technology skills required for any molecular biology work. This includes running agarose gel, plasmid preparation, nucleic acid isolation, restriction enzyme digestion, primer design, PCR and Southern hybridization. They also learn to perform recent techniques such as bisulphite conversion of DNA for methylation analysis. The students also get hands-on training on several bioinformatics tools such as ClustalW, BLAST, in-silico protein analysis, phylogenetic analysis and homology modeling.

GENOE206 Genetics in Crop Improvement and Human Health
This open elective course will preferably be open to students of discipline other than Genetics. This would provide a snapshot of the contribution and indispensable role of classical and contemporary genetic tools in improvement of overall life quality. In addition to developing concise understanding on fundamental aspects of genetic analysis, the students would also study about various breeding and genetic approaches for crop improvement. The students would also cultivate perception about the modern approaches for genetic analysis of human disorders, disease modeling in various model organisms and the available strategies for the management of genetic disorders.

GENCC301 Microbial Genetics
This paper deals with the strength of microbial genetics: both prokaryotic as well as eukaryotic systems. . Current molecular tools involved in microbial genetic analysis such as construction of vectors, artificial chromosome systems and genome editing tools are also covered.

GENCC302 Human Genetics
This introductory course attempts to walk the students through concepts of classical human genetics and advanced molecular genetics. Application of mapping tools, cloning strategies and next generation sequencing technology culminating in new/current knowledge on genetic variations in health and disease across populations and their clinical/diagnostic implications are dealt with.

GENCC303 Plant Genetics and Breeding
This course primarily deals with how to undertake plant genome analysis and gene mapping through the use of DNA markers and how this information could be utilized in bringing the efficiencies in selection methods of plant breeding and gene isolation through forward genetics approach.

GENCC304 Plant Tissue Culture and Transgenic Technology
This course is designed to provide students with specialized knowledge of the theory and practical skills of plant tissue culture, somatic cell genetics and genetic engineering relevant to crop improvement.

GENCC305 Experiments in Genetics- III (Practicals based on theory)
Study of gene expression is performed to achieve phenotypic and biochemical characterization of wild type and mutant E. coli and yeast strains. Students are taught to work with phages and yeast. Preparation of human lymphocyte metaphase chromosomes, karyotypes and chromosome banding of diagnostic value are taught. Additionally, genotyping using PCR–restriction fragment length polymorphism and sequencing methods are also a feature of the hands-on practicals. A field trip to a plant breeding station is a popular practical exposure among the students. Plant tissue culture is extensively taught and individually performed by the students.

GENCC401 Developmental Biology and Immunology
The course envisages giving an insight into how developmental patterns arise using examples from different model systems and highlighting regulatory networks involved in these processes.
The immunology course provides a comprehensive overview of basic immunology, innate immune responses, followed by a study of the main aspects of acquired immunity and genetics of antibody development.

GENCC402 Project Work
This course provides hands-on experience to the students about handling a research problem independently. Additionally, they develop work presentation and communication skills.

GENEC403 to GENEC409 Elective courses
This covers teaching specialized courses on the advances in specialized fields of genetics in various model systems used in research.

Programme Structure


  Semester Semester
Part I First Year Semester I Semester II
Part II Second Year Semester III Semester IV
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