Jagreet Kaur

 

Research Focus

Plants are prone to attack by a variety of pathogens which cause a significant loss in agricultural yield. Alternaria brassicae and Sclerotinia sclerotiorum are the major fungal pathogens that infect Brassica juncea and cause Alternaria leaf blight and stem rot, respectively. Our lab is interested in understanding the mechanisms underlying plant resistance/susceptibility to these necrotrophic fungi.We are employing genetic and molecular approaches for identification and functional analysis of novel factors that determine plant susceptibility and/or resistance to Alternaria and Sclerotinia infection.

a) Discover and analyze the function of genes involved in disease resistance to foliar fungal pathogen Alternaria brassicae: Multiple approaches are being pursued to find the genetic determinants of resistance in the Arabidopsis accessions. QTL mapping followed by I) Positional cloning, an d II) Association mapping

b) Identification of pathogen responsive promoter elements by enhancer traps screen for driving defense gene expression in crop plants to improve disease resistance.

c) Role of Arabidopsis Non symbiotic Globin in pathogen response: The role of the “plant non-symbiotic hemoglobin”, is hypothesized in abiotic stress such as hypoxia and cold stress. Arabidopsis thaliana has 3 non-symbiotic globins AHb1, Ahb2 and Ahb3. Using a multi-disciplinary approach we address the physiological relevance of the non-symbiotic class of globins. Ahb1 and Ahb3 have been crystallized in collaboration with Dr Suman Kundu (Prof., Dept of Biochemistry, UDSC) and Dr Pravindra Kumar (IIT Roorkee). Further, physiological role of these proteins in disease resistance is being evaluated.  

Lab Members:

1. Sayanti Mandal : PhD  student (Degree Awarded)                                             

2. Sivasubramanian R : PhD student  (Thesis Submitted)

3. Nitika Mukhi : PhD student (Thesis Submitted)

4. Rashmi Verma: PhD student

5. Amit Kesarwani : Project JRF

6. Tanupriya: Project JRF

7. Mr. Mukesh Mahato  (Lab help)

Publications:

Mukhi N, Dhindwal S, Uppal S, Kapoor A, Arya R, Kumar P, Kaur J, Kundu S. (2016)Structural and Functional Significance of the N- and C-Terminal Appendages in Arabidopsis Truncated Hemoglobin. Biochemistry.29;55(12):1724-40. doi: 10.1021/acs.biochem.5b01013. Epub 2016 Mar 7.
 
Mukhi N, Dhindwal S, Uppal S, Kumar P, Kaur J, Kundu S. (2013) X-ray Crystallographic Structural Characteristics of Arabidopsis Hemoglobin I and their Functional Implications. Biochem Biophys Acta. 2013 Feb 25. doi:pii: S1570-9639(13)00087-3. 10.1016/j.bbapap.2013.02.024.
 
Stuttmann J, Hubberten HM, Rietz S, Kaur J, Muskett P, Guerois R, Bednarek P, Hoefgen R, Parker JE. (2011) Perturbation of Arabidopsis amino acid metabolism causes incompatibility with the adapted biotrophic pathogen Hyaloperonospora arabidopsidis. Plant Cell 23(7):2788-803
 
Vijaybhaskar V., Subbiah V.,  Kaur J., VijayaKumari P. and Siddiqi, I. (2008) Identification of a root-specific glycosyltransferase from Arabidopsis and characterization of its promoter. J Biosci. 33(2):185-93.
 
Kaur, J. , Sabestian, J. and Siddiqi I. (2006) The Arabidopsis-mei2-like genes play a role in meiosis and vegetative growth in Arabidopsis. Plant Cell 18(3):545-59
 
Reddy, T.V*, Kaur, J.*, Agashe,B.*,Sundaresan,V., and Siddiqi, I. (2003) The DUET gene is necessary for chromosome morphogenesis and progression during male meiosis in Arabidopsis thaliana and potentially encodes a PHD finger domain.  Development:  130(24):5975-87* Equal First Authors

 

Book chapter

Sivasubramanian R., Mukhi N., and Kaur J. (2015) Arabidopsis thaliana : A model for plant research  in Plant Biology and Biotechnology: Volume II: Plant Genomics and Biotechnology, Bir Bahadur et al. (eds.) DOI 10.1007/978-81-322-2283-5_1, © Springer India 2015 Eds. 


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